Study may show ways to fight cancer
New research into the genes that control cell growth and behaviour has raised hopes of a breakthrough in understanding and tackling cancer.
An international team of scientists including experts from Cancer Research UK and Cambridge University have studied the structure of cells in yeast – with findings that may have implications for humans too.
The experts said it was the first time nearly all the genes required for reproduction of a cell and for a proper cell shape to be formed have been identified for a living organism.
The work, reported in Royal Society journal Open Biology, was carried out in yeast by studying a set of mutant strains in each of which a single gene had been deleted.
Each of these strains was examined to see if cell reproduction or cell shape was changed. In this way all the genes involved in these processes were identified.
Dr Julie Sharp, Cancer Research UK’s senior science information manager, said: “For the first time our researchers have created a complete picture of the genes that control cell growth and behaviour in yeast cells, which could reveal more about how cancer starts and develops and highlight new ways to tackle the disease.
“Research like this will be central to the work at the Francis Crick Institute, a new super-laboratory in London headed by Professor Sir Paul Nurse, where scientists will tackle major diseases such as cancer using the very latest technologies.”
The scientists, led by Dr Jacqueline Hayles at Cancer Research UK, said it was hoped the research would help to identify cell cycle and cell shape genes in other organisms, including humans.
They noted: “Failure to accurately reproduce and maintain cell shape can disrupt tissue architecture or influence cell motility and may also lead to cell death or disease.
“We have generated a genome-wide resource, cataloguing the genes that when deleted disrupt the cell cycle or cell shape in the fission yeast Schizosaccharomyces pombe. This is the first such resource that qualitatively describes a near complete set of genes required.”
Have you got a health question?
We've teamed up with AXA PPP healthcare to bring you articles, information and tips from their clinical teams on a wide range of health topics. And if you have a question of your own, their, "Ask the Expert" service allows you to ask the team of friendly, experienced nurses, pharmacists and midwives about any health topic and they'll get back to you with an answer as soon as they’re able.* So if you have something that’s been bothering you, whether it concerns you or someone close to you, don’t hesitate to get in touch.
Click below to submit your query online.
* Nurses are available 24/7, 365 days a year. Midwives and pharmacists are available Monday to Friday, 8am to 8pm; Saturday, 8am to 4pm; and Sunday, 8am to 12pm.
Actual response time will depend on the nature of your enquiry and availability of appropriately qualified experts but the team will always aim to get back to you within 24 hours.
Please note that our Expert Help services are there to offer health information and support. They do not diagnose or prescribe, and are not intended to be a substitute for professional medical advice given in the context of an individual consultation.
The Press Association
Latest posts by The Press Association (see all)
- My mother’s in a care home and isolating has made her so miserable - June 30, 2020
- Diana: The style moments that made her a fashion icon - June 30, 2020
- How to keep your crops fruiting throughout summer - June 30, 2020
- Weird and wonderful butterflies and moths to spot this summer - June 29, 2020
- 7 retro iced desserts to cool down with now - June 25, 2020
Leave a Comment!
Community Terms & Conditions
These content standards apply to any and all material which you contribute to our site (contributions), and to any interactive services associated with it.
You must comply with the spirit of the following standards as well as the letter. The standards apply to each part of any contribution as well as to its whole.
be accurate (where they state facts); be genuinely held (where they state opinions); and comply with applicable law in the UK and in any country from which they are posted.
Contributions must not:
contain any material which is defamatory of any person; or contain any material which is obscene, offensive, hateful or inflammatory; or promote sexually explicit material; or promote violence; promote discrimination based on race, sex, religion, nationality, disability, sexual orientation or age; or infringe any copyright, database right or trade mark of any other person; or be likely to deceive any person; or be made in breach of any legal duty owed to a third party, such as a contractual duty or a duty of confidence; or promote any illegal activity; or be threatening, abuse or invade another’s privacy, or cause annoyance, inconvenience or needless anxiety; or be likely to harass, upset, embarrass, alarm or annoy any other person; or be used to impersonate any person, or to misrepresent your identity or affiliation with any person; or give the impression that they emanate from us, if this is not the case; or advocate, promote or assist any unlawful act such as (by way of example only) copyright infringement or computer misuse.
Nurturing a safe environment
Our Silversurfers community is designed to foster friendships, based on trust, honesty, integrity and loyalty and is underpinned by these values.
We don't tolerate swearing, and reserve the right to remove any posts which we feel may offend others... let's keep it friendly!